Mutation Datasets

Release Date: February 27, 2025

Mutation Dataset

We have annotated genetic variants from ClinVar, UK Biobank, and gnomAD using ProteinIS to determine whether amino acid changes occur at protein-protein interaction (PPI) sites. Explore these annotations through our interactive query interface or download complete datasets from the Download section.

Mutation Statistics Overview

Explore comprehensive statistics of genetic variants across different categories and data types.

Nucleotide Substitutions (AA Changes)

Amino Acid Changes

Gene Symbols

Swiss-Prot Proteins

Nucleotide Substitutions (AA Changes)

Amino Acid Changes

Gene Symbols

Swiss-Prot Proteins

Nucleotide Substitutions (AA Changes)

Amino Acid Changes

Gene Symbols

Swiss-Prot Proteins

CHROM POS REF ALT Consequence Gene Feature Gene_symbol SWISSPROT Protein_position Amino_acids canonical clin_sig SIFT_type SIFT_score Polyphen_type Polyphen_score 3Dmapper_result PPI